Liquid Boichip

Liquid biochip technology, also known as flow fluorescence technology, liquid chip technology or suspension array technology, is a new generation of high-throughput, multi-index detection technology platform developed in the post-genomic era.

Liquid biochip organically integrates coded microspheres, laser technology, applied fluid science, the latest high-speed digital signal processors and computer algorithms. It has the advantages of high throughput, multi-index, high speed, low cost, high sensitivity, good repeatability and wide linear range. It can be widely used in immunoassay, nucleic acid research, enzyme analysis, receptor and ligand recognition analysis, etc. It is also a biochip platform that is currently recognized by authorities and the medical community for clinical diagnosis.

Advantages of the Liquid Biochip Technique

Sample Diversity

Liquid chip technology can be used to detect target proteins or target nucleic acid molecules after coating proteins or nucleic acids on coding microspheres.

High Sensitivity

A sufficient amount of protein or nucleic acid molecules can be covalently coupled to the surface of each microsphere, and a large number of target molecules can be bound, and the fluorescence detection signal is strong and the sensitivity is high.

Rapid Processing

The homogeneous reaction in liquid environment can keep the conformation of biomolecules unchanged, which is more conducive to the binding of biomolecules, and the reaction time is short and the speed is fast.

High Flexibility

Liquid chip technology can flexibly add well-coated microspheres for detection according to the type of detection target, which has good flexibility.

High Specificity

At the same time, the hybridization signal intensity and fluorescence coding signal of the microspheres in a specific size range after laser excitation were analyzed, and the detection results were highly specific.

Multiplexes Biodetection

Requiring only a minimal sample (less than 200 μL) for testing, this technique can precisely measure multiple analytes (up to 100) in a single
sample.

Consistent Repeatability

Due to the nearly homogeneous reaction, the repeatability (up to 1000 times) for the same target
is excellent

Cost Saving

Based on great test efficiency, the technique minimizes costs related to reagents,consumables, and instrumentation.

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